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Article

Regulation of KCNQ4 potassium channel prepulse dependence and current amplitude by SGK1 in Xenopus oocytes.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology - 1 Jan 2005

Seebohm Guiscard, Strutz-Seebohm Nathalie, Baltaev Ravshan, Korniychuk Ganna, Knirsch Martina, Engel Jutta, Lang Florian

Abstract excerpt

The KCNQ gene family comprises voltage-gated potassium channels expressed in epithelial tissues (KCNQ1, KCNQ5), inner ear structures (KCNQ1, KCNQ4) and the brain (KCNQ2-5). KCNQ4 is expressed in inner and outer hair cells of the inner ear where it determines electrical excitability. Accordingly, loss of function mutations of the KCNQ4 gene cause hearing loss. Several K+ channels including the closely related...

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Source

Identifiers

PMID: 16301825
DOI: 10.1159/000089851

Genes

KCNQ4
SGK1
KCNQ1
KCNQ2
KCNQ5

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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