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Article

Activation of KCNQ4 as a Therapeutic Strategy to Treat Hearing Loss.

International journal of molecular sciences - 2 Mar 2021

Rim John Hoon, Choi Jae Young, Jung Jinsei, Gee Heon Yung

Abstract excerpt

Potassium voltage-gated channel subfamily q member 4 (KCNQ4) is a voltage-gated potassium channel that plays essential roles in maintaining ion homeostasis and regulating hair cell membrane potential. Reduction of the activity of the KCNQ4 channel owing to genetic mutations is responsible for nonsyndromic hearing loss, a typically late-onset, initially high-frequency loss progressing over time. In addition,...

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Identifiers

PMID: 33801540
DOI: 10.3390/ijms22052510
PMCID: PMC7958948

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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