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Article

Functional coassembly of KCNQ4 with KCNE-beta- subunits in Xenopus oocytes.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology - 1 Jan 2006

Strutz-Seebohm Nathalie, Seebohm Guiscard, Fedorenko Olga, Baltaev Ravshan, Engel Jutta, Knirsch Martina, Lang Florian

Abstract excerpt

The KCNQ gene family comprises voltage-gated potassium channels expressed in epithelial tissues (KCNQ1, KCNQ5), inner ear structures (KCNQ1, KCNQ4) and the brain (KCNQ2-5). KCNQ4 is expressed in inner and outer hair cells of the inner ear where it influences electrical excitability and cell survival. Accordingly, loss of function mutations of the KCNQ4 gene cause hearing loss in humans and functional k.o.-mice...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16914890
DOI: 10.1159/000095158

Genes

KCNQ4
KCNQ1
KCNQ2
KCNQ5

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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