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Article

Association of the serum and glucocorticoid regulated kinase (sgk1) gene with QT interval.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology - 1 Jan 2004

Busjahn Andreas, Seebohm Guiscard, Maier Gottlieb, Toliat Mohammad Reza, Nürnberg Peter, Aydin Atakan, Luft Friedrich C, Lang Florian

Abstract excerpt

The serum and glucocorticoid inducible kinase (SGK1) is well known to up-regulate the renal epithelial Na(+) channel ENaC. Excessive SGK1 activity would be expected to cause renal Na(+) retention and blood pressure increase. Certain polymorphisms of the SGK1 gene (E8CC/CT;I6CC) are indeed associated with moderately enhanced blood pressure. We have recently disclosed another function of SGK1, i.e. the stimulation...

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Source

Identifiers

PMID: 15107590
DOI: 10.1159/000078105

Genes

SGK1
KCNQ1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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