Article
Molecular basis of voltage-dependent potassium currents in porcine granulosa cells.
Molecular pharmacology - 1 Jan 2002
Mason Diane E, Mitchell Kathy E, Li Yan, Finley Melissa R, Freeman Lisa C
Abstract excerpt
The major objective of this study was to elucidate the molecular bases for K(+) current diversity in porcine granulosa cells (GC). Two delayed rectifier K(+) currents with distinct electrophysiological and pharmacological properties were recorded from porcine GC by using whole-cell patch clamp: 1) a slowly activating, noninactivating current (I(Ks)) antagonized by clofilium, 293B, L-735,821, and L-768,673; and 2)...
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