Article
Associations between GPX1 Pro198Leu polymorphism, erythrocyte GPX activity, alcohol consumption and breast cancer risk in a prospective cohort study.
Carcinogenesis - 1 Apr 2006
Ravn-Haren Gitte, Olsen Anja, Tjønneland Anne, Dragsted Lars O, Nexø Bjørn A, Wallin Håkan, Overvad Kim, Raaschou-Nielsen Ole, Vogel Ulla
Abstract excerpt
Breast cancer may be related to oxidative stress. Breast cancer patients have been reported to have lower antioxidant enzyme activity than healthy controls and the polymorphism GPX1 Pro198Leu has been associated with risk of lung and breast cancer. The purpose of the present nested case-control study was to determine whether GPX1 Pro198Leu and glutathione peroxidase (GPX) activity in prospectively collected blood...
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