Article
Association between glutathione peroxidase 1 codon 198 variant and the occurrence of breast cancer in Rwanda.
Molecular genetics & genomic medicine - 1 Mar 2018
Habyarimana Thierry, Bakri Youssef, Mugenzi Pacifique, Mazarati Jean Baptiste, Attaleb Mohammed, El Mzibri Mohammed
Abstract excerpt
BACKGROUND: Glutathione peroxidase 1 gene (GPX1) is one of the antioxidant enzyme that remove the reactive oxygen species in a continuous process. Since the identification of a well-characterized functional polymorphism named p.Pro198Leu (rs1050450 C>T) in GPX1 gene, abundant studies have evaluated the association between p.Pro198Leu polymorphism and tumor risk in diverse population. But, the available results...
Topics
- Adult
- Alleles
- Base Sequence
- Breast Neoplasms
- Breast Neoplasms, Male
- Case-Control Studies
- Codon
- Female