Association between glutathione peroxidase 1 codon 198 variant and the occurrence of breast cancer in Rwanda.

doi:10.1002/mgg3.367

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Article

Association between glutathione peroxidase 1 codon 198 variant and the occurrence of breast cancer in Rwanda.

Molecular genetics & genomic medicine - 1 Mar 2018

Habyarimana Thierry, Bakri Youssef, Mugenzi Pacifique, Mazarati Jean Baptiste, Attaleb Mohammed, El Mzibri Mohammed

Abstract excerpt

BACKGROUND: Glutathione peroxidase 1 gene (GPX1) is one of the antioxidant enzyme that remove the reactive oxygen species in a continuous process. Since the identification of a well-characterized functional polymorphism named p.Pro198Leu (rs1050450 C>T) in GPX1 gene, abundant studies have evaluated the association between p.Pro198Leu polymorphism and tumor risk in diverse population. But, the available results...

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PMID: 29411539
DOI: 10.1002/mgg3.367
PMCID: PMC5902397

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GPX1

Variants

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