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Article

Lipid peroxidation and glutathione peroxidase activity relationship in breast cancer depends on functional polymorphism of GPX1.

BMC cancer - 7 Oct 2015

Jablonska Ewa, Gromadzinska Jolanta, Peplonska Beata, Fendler Wojciech, Reszka Edyta, Krol Magdalena B, Wieczorek Edyta, Bukowska Agnieszka, Gresner Peter, Galicki Michal, Zambrano Quispe Oskar, Morawiec Zbigniew, Wasowicz Wojciech

Abstract excerpt

BACKGROUND: Since targeting oxidative stress markers has been recently recognized as a novel therapeutic target in cancer, it is interesting to investigate whether genetic susceptibility may modify oxidative stress response in cancer. The aim of this study was to elucidate whether genetic polymorphism in the antioxidant enzymes is associated with lipid peroxidation in breast cancer. METHODS: We conducted a study...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26446998
DOI: 10.1186/s12885-015-1680-4
PMCID: PMC4597452

Genes

GPX1
GPX4
SOD1
SOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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