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Article

GPx-1 polymorphism (rs1050450) contributes to tumor susceptibility: evidence from meta-analysis.

Journal of cancer research and clinical oncology - 1 Oct 2011

Chen Jiawei, Cao Qiang, Qin Chao, Shao Pengfei, Wu Yilong, Wang Meilin, Zhang Zhengdong, Yin Changjun

Abstract excerpt

PURPOSE: Accumulating evidences implicate the selenium-containing cytosolic glutathione peroxidase, GPx-1, as a determinant of cancer risk and a mediator of the chemopreventive properties of selenium. Since the identification of a well-characterized functional polymorphism named Pro198Leu (rs1050450 C>T) in GPx-1, abundant studies have evaluated the association between Pro198Leu polymorphism and tumor risk in...

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PMID: 21842217
DOI: 10.1007/s00432-011-1033-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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