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Article

GPX1 Pro198Leu polymorphism and breast cancer risk: a meta-analysis.

Breast cancer research and treatment - 1 Nov 2010

Hu Jia, Zhou Guo-Wu, Wang Ning, Wang Ya-Jie

Abstract excerpt

A genetic polymorphism at codon 198 in the human glutathione peroxidase 1 gene was reported to be associated with several cancers. However, this relationship remains controversial, especially in breast cancer. For better understanding the effect of GPX1 Pro198Leu polymorphism on breast cancer, a meta-analysis was performed. By searching relevant literatures, a total of six case-control studies, containing 5,509...

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Identifiers

PMID: 20306294
DOI: 10.1007/s10549-010-0841-z

Genes

GPX1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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GPX1 Pro198Leu polymorphism and breast cancer risk: a meta-analysis.PMID 20306294Read ↗

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GPX1 gene Pro200Leu polymorphism, erythrocyte GPX activity, and cancer risk.Semantic proximity Read ↗

No association between GPX1 Pro198Leu and breast cancer risk.Semantic proximity Read ↗

Associations between GPX1 Pro198Leu polymorphism, erythrocyte GPX activity, alcohol consumption and breast cancer risk in a prospective cohort study.Semantic proximity Read ↗

Association between genetic variants in glutathione peroxidase 1 gene and risk of prostate cancer: a meta-analysis.Semantic proximity Read ↗

Lipid peroxidation and glutathione peroxidase activity relationship in breast cancer depends on functional polymorphism of GPX1.Semantic proximity Read ↗

GSTT1 and GSTP1 polymorphisms and breast cancer risk: a meta-analysis.Semantic proximity Read ↗

No association between glutathione peroxidase Pro198Leu polymorphism and breast cancer risk.Semantic proximity Read ↗

Association between GPx1 Pro198Leu polymorphism, GPx1 activity and plasma selenium concentration in humans.Semantic proximity Read ↗

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