Article
Association between GPX1 Pro189Leu polymorphism and the occurrence of bladder cancer in Morocco.
Cellular and molecular biology (Noisy-le-Grand, France) - 30 Dec 2016
Hadami K, Ameziane El Hassani R, Ameur A, Dakka N, Abbar M, Al Bouzidi A, Attaleb M, El Mzibri M
Abstract excerpt
Worldwide, Bladder cancer is the most frequent male malignancy. It is the third most common male malignancy in Morocco. The risk factors for developing bladder cancer are multiples including dietary conditions, environmental exposure and oxidative stress. GPX1 gene encoding for the human cellular antioxidant enzyme glutathione peroxidase1 is a key factor in the cell detoxification process. GPX1 Pro198Leu...
Topics
- Adult
- Aged
- Alleles
- Base Sequence
- Case-Control Studies
- DNA Mutational Analysis
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Glutathione Peroxidase