Article
SNP selection for association studies: maximizing power across SNP choice and study size.
Annals of human genetics - 1 Nov 2005
Pardi F, Lewis C M, Whittaker J C
Abstract excerpt
Selection of single nucleotide polymorphisms (SNPs) is a problem of primary importance in association studies and several approaches have been proposed. However, none provides a satisfying answer to the problem of how many SNPs should be selected, and how this should depend on the pattern of linkage disequilibrium (LD) in the region under consideration. Moreover, SNP selection is usually considered as independent...
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