Article
Optimal selection of SNP markers for disease association studies.
Human heredity - 1 Jan 2004
Halldórsson Bjarni V, Istrail Sorin, De La Vega Francisco M
Abstract excerpt
Genetic association studies with population samples hold the promise of uncovering the susceptibility genes underlying the heritability of complex or common disease. Most association studies rely on the use of surrogate markers, single-nucleotide polymorphism (SNP) being the most suitable due to...
Topics
- Algorithms
- Alleles
- Genetic Diseases, Inborn
- Genetic Markers
- Genetic Predisposition to Disease
- Genetic Techniques
- Genotype
- Haplotypes
- Humans
- Linkage Disequilibrium
- Models, Genetic
- Models, Statistical