Article
SNP subset selection for genetic association studies.
Annals of human genetics - 1 Nov 2003
Byng M C, Whittaker J C, Cuthbert A P, Mathew C G, Lewis C M
Abstract excerpt
Association studies for disease susceptibility genes rely on the high density of SNPs within candidate genes. However, the linkage disequilibrium between SNPs imply that not all SNPs identified in the candidate region need be genotyped. Here we develop several approaches to SNP subset selection, which can substantially reduce the number of SNPs to be genotyped in an association study. We apply clustering...
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