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Article

A grid-search algorithm for optimal allocation of sample size in two-stage association studies.

Journal of human genetics - 1 Jan 2007

Wen S H, Hsiao C K

Abstract excerpt

Multiple testing occurs commonly in genome-wide association studies with dense SNPs map. With numerous SNPs, not only the genotyping cost and time increase dramatically, many family wise error rate (FWER) controlling methods may fail for being too conservative and of less power when detecting SNPs associated with disease is of interest. Recently, several powerful two-stage strategies for multiple testing have...

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PMID: 17603750
DOI: 10.1007/s10038-007-0159-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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