Article
Comparison of strategies for selecting single nucleotide polymorphisms for case/control association studies.
Human genetics - 1 Aug 2003
Huang Qiqing, Fu Yun-Xin, Boerwinkle Eric
Abstract excerpt
It is widely believed that a subset of single nucleotide polymorphisms (SNPs) is able to capture the majority of the information for genotype-phenotype association studies that is contained in the complete compliment of genetic variations. The question remains, how does one select that particular subset of SNPs in order to maximize the power of detecting a significant association? In this study, we have used a...
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