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Article

Tests of association between quantitative traits and haplotypes in a reduced-dimensional space.

Annals of human genetics - 1 Nov 2005

Sha Qiuying, Dong Jianping, Jiang Renfang, Zhang Shuanglin

Abstract excerpt

Candidate gene association tests are currently performed using several intragenic SNPs simultaneously, by testing SNP haplotype or genotype effects in multifactorial diseases or traits. The number of haplotypes drastically increases with an increase in the number of typed SNPs. As a result, large numbers of haplotypes will introduce large degrees of freedom in haplotype-based tests, and thus limit the power of...

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PMID: 16266410
DOI: 10.1111/j.1529-8817.2005.00216.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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