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Article

A principal components-based clustering method to identify variants associated with complex traits.

Human heredity - 1 Jan 2011

Black Mary Helen, Watanabe Richard M

Abstract excerpt

BACKGROUND: Multivariate methods ranging from joint SNP to principal components analysis (PCA) have been developed for testing multiple markers in a region for association with disease and disease-related traits. However, these methods suffer from low power and/or the inability to identify the subset of markers contributing to evidence for association under various scenarios. METHODS: We introduce orthoblique...

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Identifiers

PMID: 21389731
DOI: 10.1159/000323567
PMCID: PMC3089426

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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