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Article

A partial least-square approach for modeling gene-gene and gene-environment interactions when multiple markers are genotyped.

Genetic epidemiology - 1 Jan 2009

Wang Tao, Ho Gloria, Ye Kenny, Strickler Howard, Elston Robert C

Abstract excerpt

Genetic association studies achieve an unprecedented level of resolution in mapping disease genes by genotyping dense single nucleotype polymorphisms (SNPs) in a gene region. Meanwhile, these studies require new powerful statistical tools that can optimally handle a large amount of information provided by genotype data. A question that arises is how to model interactions between two genes. Simply modeling all...

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PMID: 18615621
DOI: 10.1002/gepi.20351
PMCID: PMC2700837

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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