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Article

A hierarchical clustering method for dimension reduction in joint analysis of multiple phenotypes.

Genetic epidemiology - 1 Jun 2018

Liang Xiaoyu, Sha Qiuying, Rho Yeonwoo, Zhang Shuanglin

Abstract excerpt

Genome-wide association studies (GWAS) have become a very effective research tool to identify genetic variants of underlying various complex diseases. In spite of the success of GWAS in identifying thousands of reproducible associations between genetic variants and complex disease, in general, the association between genetic variants and a single phenotype is usually weak. It is increasingly recognized that joint...

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PMID: 29682782
DOI: 10.1002/gepi.22124
PMCID: PMC5980772

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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