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Article

pHCR: a parallel haplotype configuration reduction algorithm for haplotype interaction analysis.

Journal of human genetics - 1 Nov 2009

Makarasara Wattanan, Kumasaka Natsuhiko, Assawamakin Anunchai, Takahashi Atsushi, Intarapanich Apichart, Ngamphiw Chumpol, Kulawonganunchai Supasak, Ruangrit Uttapong, Fucharoen Suthat, Kamatani Naoyuki, Tongsima Sissades

Abstract excerpt

Finding gene interaction models is one of the most important issues in genotype-phenotype association studies. This paper presents a model-free nonparametric statistical interaction analysis known as Parallel Haplotype Configuration Reduction (pHCR). This technique extends the original Multifactor Dimensionality Reduction (MDR) algorithm by using haplotype contribution values (c-values) and a haplotype...

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PMID: 19927163
DOI: 10.1038/jhg.2009.85

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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