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Article

Efficiency and power in genetic association studies.

Nature genetics - 1 Nov 2005

de Bakker Paul I W, Yelensky Roman, Pe'er Itsik, Gabriel Stacey B, Daly Mark J, Altshuler David

Abstract excerpt

We investigated selection and analysis of tag SNPs for genome-wide association studies by specifically examining the relationship between investment in genotyping and statistical power. Do pairwise or multimarker methods maximize efficiency and power? To what extent is power compromised when tags are selected from an incomplete resource such as HapMap? We addressed these questions using genotype data from the...

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PMID: 16244653
DOI: 10.1038/ng1669

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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