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Article

The value of gene-based selection of tag SNPs in genome-wide association studies.

European journal of human genetics : EJHG - 1 Nov 2006

Wiltshire Steven, de Bakker Paul I W, Daly Mark J

Abstract excerpt

Genome-wide association scans are rapidly becoming reality, but there is no present consensus regarding genotyping strategies to optimise the discovery of true genetic risk factors. For a given investment in genotyping, should tag SNPs be selected in a gene-centric manner, or instead, should coverage be optimised based on linkage disequilibrium alone? We explored this question using empirical data from the...

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PMID: 16804554
DOI: 10.1038/sj.ejhg.5201678

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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