Article
Evaluating and improving power in whole-genome association studies using fixed marker sets.
Nature genetics - 1 Jun 2006
Pe'er Itsik, de Bakker Paul I W, Maller Julian, Yelensky Roman, Altshuler David, Daly Mark J
Abstract excerpt
Emerging technologies make it possible for the first time to genotype hundreds of thousands of SNPs simultaneously, enabling whole-genome association studies. Using empirical genotype data from the International HapMap Project, we evaluate the extent to which the sets of SNPs contained on three whole-genome genotyping arrays capture common SNPs across the genome, and we find that the majority of common SNPs are...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.