Article
A comparison of tagging methods and their tagging space.
Human molecular genetics - 15 Sept 2005
Ke Xiayi, Miretti Marcos M, Broxholme John, Hunt Sarah, Beck Stephan, Bentley David R, Deloukas Panos, Cardon Lon R
Abstract excerpt
Single-nucleotide polymorphism (SNP) tagging is widely used as a way of saving genotyping costs in association studies. A number of different tagging methods have been developed to reduce the number of markers to be genotyped while maintaining power for detecting effects on non-assayed SNPs. How the different methods perform in different settings, the degree to which they overlap and share common tags and how...
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