Article
Detection of FLT3 gene and FLT3/ITD mutation by polymerase chain reaction-single-strand conformation polymorphism in patients with acute lymphoblastic leukemia.
Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA - 1 Oct 2005
Xu Bing, Li Lin, Tang Jia-hong, Zhou Shu-yun
Abstract excerpt
OBJECTIVE: To analyze Fms-like tyrosine kinase 3 (FLT3) gene and FLT3 internal tandem duplication (ITD) mutation in acute lymphoblastic leukemia (ALL) patients of different immunological subtypes. METHODS: Polymerase chain reaction-single-strand conformation polymorphism (PCR-SSCP) was used to detect FLT3 gene and FLT3/ITD mutation in 63 ALL cases. RESULTS: Among the 63 ALL cases, FLT3 gene was detected in 41...
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