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Article

Lack of FLT3-ITD in Tunisian childhood acute lymphoblastic leukemia.

African health sciences - 1 Jun 2022

Frikha Rim, Abdellaoui Nawel, Kassar Olfa, Rebai Tarek

Abstract excerpt

Background: The fms-like tyrosine kinase 3 (FLT3) gene belong to the class III receptor tyrosine kinases witch is predominantly expressed on hematopoietic progenitor cells, and plays an important role in haematopoiesis. Targeting the FMS-like tyrosine kinase receptor-3 (FLT3) in acute leukemia is mainly important. Therefore, activating mutations in FLT3, primarily the FLT3-internal tandem duplication (FLT3-ITD),...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36407352
DOI: 10.4314/ahs.v22i2.35
PMCID: PMC9652637

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