Article
Fms-like tyrosine kinase 3 mutations in childhood acute leukemias and their association with prognosis.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2010
Karabacak Bircan Hizli, Erbey Fatih, Bayram Ibrahim, Yilmaz Sema, Acipayam Can, Kilinç Yurdanur, Tanyeli Atila
Abstract excerpt
INTRODUCTION: In recent years, Fms-like tyrosine kinase (FLT) 3 has been the subject of several studies as a prognostic marker. OBJECTIVE: In this study, the presence of FLT3 mutations in childhood acute leukemias patients and their association with prognosis were investigated. MATERIALS AND METHODS: A total of 120 patients, 80 with acute lymphoblastic leukemia (ALL) and 40 with acute myeloblastic leukemia (AML),...
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