Article
Fms-like tyrosine kinase (FLT) 3 and FLT3 internal tandem duplication in different types of adult leukemia: analysis of 147 patients.
Croatian medical journal - 1 Oct 2008
Peng Hong-Ling, Zhang Guang-Sen, Gong Fan-Jie, Shen Jian-Kai, Zhang Yang, Xu Yun-Xiao, Zheng Wen-Li, Dai Chong-Wen, Pei Min-Fei, Yang Jun-Jie
Abstract excerpt
AIM: To assess the expression level of fms-like tyrosine kinase 3 (FLT3), the incidence of FLT3/internal tandem duplications (ITD) mutation, and prognostic value of FLT3 changes in different types of adult leukemia. METHODS: Bone marrow mononuclear cells were isolated from 147 adult patients with leukemia. Reverse transcriptase polymerase chain reaction (PCR) was used to screen FLT3/ITD mutation and quantitative...
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