Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Chimpanzee DC-SIGN alleles predict the existence of A and B isoforms, but do not support a role for resistance to HIV infection.

AIDS research and human retroviruses - 1 Sept 2005

Santos Patrícia R, Michel-Salzat Alice, Butor Cécile

Abstract excerpt

We report here the gene sequence for DC-SIGN (CD209) from chimpanzees. DC-SIGN is a C-type lectin expressed by dendritic cells. It is involved in DC-T cell interactions as well as in HIV-1 and SIV transmission. We have cloned two new alleles for chimpanzee DC-SIGN. The coding sequences are highly homologous to the two previously described chimpanzee alleles. We confirm the existence of a polymorphism within the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Adhesion Molecules
Share to Dendritic Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HIV Infections

Share to Immunity, Innate

Share to Lectins, C-Type

Share to Pan troglodytes

Share to Protein Isoforms

Share to Receptors, Cell Surface

Source

Identifiers

PMID: 16218808
DOI: 10.1089/aid.2005.21.820

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Chimpanzee DC-SIGN alleles predict the existence of A and B isoforms, but do not support a role for resistance to HIV infection.PMID 16218808Read ↗

Gene for chinese rhesus macaque DC-SIGN predicts the existence of A but not B isoforms of the protein.Semantic proximity Read ↗

Risk for HIV-1 infection is not associated with repeat-region polymorphism in the DC-SIGN neck domain and novel genetic DC-SIGN variants among North Indians.Semantic proximity Read ↗

The tandem-repeat polymorphism of the DC-SIGNR gene does not affect the susceptibility to HIV infection and the progression to AIDS.Semantic proximity Read ↗

DC-SIGN and DC-SIGNR polymorphic variants in Northern Asian Indians.Semantic proximity Read ↗

Polymorphic variants in DC-SIGN, DC-SIGNR and SDF-1 in high risk seronegative and HIV-1 patients in Northern Asian Indians.Semantic proximity Read ↗

Naturally-occurring genetic variants in human DC-SIGN increase HIV-1 capture, cell-transfer and risk of mother-to-child transmission.Semantic proximity Read ↗

Protective role of DC-SIGN (CD209) neck-region alleles with <5 repeat units in HIV-1 transmission.Semantic proximity Read ↗

Polymorphisms in DC-SIGN and L-SIGN genes are associated with HIV-1 vertical transmission in a Northeastern Brazilian population.Semantic proximity Read ↗

Determination of DC-SIGN and DC-SIGNR repeat region variations.Semantic proximity Read ↗

DC-SIGN and DC-SIGNR genetic diversity among different ethnic populations: potential implications for pathogen recognition and disease susceptibility.Semantic proximity Read ↗

The nine-repeat DC-SIGNR isoform is associated with increased HIV-RNA loads and HIV sexual transmission.Semantic proximity Read ↗

Towards a crucial role for DC-SIGN in tuberculosis and beyond.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.