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Article

The tandem-repeat polymorphism of the DC-SIGNR gene does not affect the susceptibility to HIV infection and the progression to AIDS.

Clinical immunology (Orlando, Fla.) - 1 Apr 2003

Lichterfeld Mathias, Nischalke Hans Dieter, van Lunzen Jan, Söhne Jennifer, Schmeisser Norbert, Woitas Rainer, Sauerbruch Tilman, Rockstroh Jürgen K, Spengler Ulrich

Abstract excerpt

DC-SIGNR is a C-type lectin that functions as a transreceptor for HIV-1. The exon 4 of the DC-SIGNR gene comprises a variable number of 69-bp tandem repeats, encoding for parts of the extracellular protein domain. Here, we analyzed the relevance of this gene polymorphism for the interindividual transmission of HIV-1 and the progression to AIDS. A cross-sectional comparison between HIV-1-infected patients (n =...

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Share to Acquired Immunodeficiency Syndrome
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to DNA, Viral

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Source

Identifiers

PMID: 12738250
DOI: 10.1016/s1521-6616(02)00050-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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