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Article

Naturally-occurring genetic variants in human DC-SIGN increase HIV-1 capture, cell-transfer and risk of mother-to-child transmission.

PloS one - 1 Jan 2012

Boily-Larouche Geneviève, Milev Miroslav P, Zijenah Lynn S, Labbé Annie-Claude, Zannou Djimon M, Humphrey Jean H, Ward Brian J, Poudrier Johanne, Mouland Andrew J, Cohen Eric A, Roger Michel

Abstract excerpt

BACKGROUND: Mother-to-child transmission (MTCT) is the main cause of HIV-1 infection in children worldwide. Dendritic cell-specific ICAM-3 grabbing-nonintegrin (DC-SIGN, also known as CD209) is an HIV-1 receptor that enhances its transmission to T cells and is expressed on placental macrophages....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22808239
DOI: 10.1371/journal.pone.0040706
PMCID: PMC3393705

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22808239-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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