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Article

Polymorphisms in DC-SIGN and L-SIGN genes are associated with HIV-1 vertical transmission in a Northeastern Brazilian population.

Human immunology - 1 Nov 2012

da Silva Ronaldo Celerino, Segat Ludovica, Zanin Valentina, Arraes Luiz Claudio, Crovella Sergio

Abstract excerpt

DC-SIGN and L-SIGN are receptors expressed on specialized macrophages in decidua, (Hofbauer and placental capillary endothelial cells), known to interact with several pathogens, including HIV-1. To disclose the possible involvement of these molecules in the susceptibility to HIV vertical transmission, we analyzed DC-SIGN and L-SIGN gene single nucleotide polymorphisms (SNPs) in 192 HIV-1 positive children and 58...

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Identifiers

PMID: 22902397
DOI: 10.1016/j.humimm.2012.07.338

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Polymorphisms in DC-SIGN and L-SIGN genes are associated with HIV-1 vertical transmission in a Northeastern Brazilian population.PMID 22902397Read ↗

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