Article
Gene for chinese rhesus macaque DC-SIGN predicts the existence of A but not B isoforms of the protein.
AIDS research and human retroviruses - 1 Sept 2002
Santos Patrícia R, Petitprez Karine, Butor Cécile
Abstract excerpt
We report here the gene for DC-SIGN from Chinese rhesus macaques. DC-SIGN is a C-type lectin expressed by dendritic cells (DCs). It is involved in the interaction of DCs with T cells, and in transmission to T cells of HIV-1 and SIV. Alternative splicing in human DC-SIGN yields A and B isoforms of the protein. The overall organization of the rhesus macaque gene is similar to that of the human gene. Translation of...
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