Article
The nine-repeat DC-SIGNR isoform is associated with increased HIV-RNA loads and HIV sexual transmission.
Journal of clinical immunology - 1 May 2010
Xu Lijun, Li Qinguang, Ye Hanhui, Zhang Qiyun, Chen Huicong, Huang Fan, Chen Ronghua, Zhou Rui, Zhou Wen, Xia Pincang, Chen Yi, Pan Chen
Abstract excerpt
OBJECTIVES: Determine if different DC-SIGNR genotypes/alleles correlated with HIV susceptibility in the context of the HIV mode of infection, CD4+ T cell counts and blood HIV RNA loads. METHODS: One hundred forty-five HIV infected individuals and 187 uninfected healthy controls were recruited to observe whether DC-SIGNR genotypes/alleles were correlated with HIV susceptibility, CD4+ T cell numbers and HIV-RNA...
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