Article
Towards a crucial role for DC-SIGN in tuberculosis and beyond.
Trends in microbiology - 1 Sept 2006
Neyrolles Olivier, Gicquel Brigitte, Quintana-Murci Lluís
Abstract excerpt
The C-type lectin DC-SIGN has recently received considerable attention in the context of tuberculosis and other infectious diseases. Clinical investigations, together with genetic association studies, strongly support the notion that variation in the level of expression of DC-SIGN - but not changes in the structure of the protein - might have a strong impact on the susceptibility to and pathogenesis of several...
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