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Article

Tests for the presence of two linked disease susceptibility genes.

Genetic epidemiology - 1 Dec 2005

Biernacka Joanna M, Sun Lei, Bull Shelley B

Abstract excerpt

For diseases with complex genetic etiology, more than one susceptibility gene may exist in a single chromosomal region. Under explicit assumptions about the number of disease genes in a region, generalized estimating equations (GEE) can be used to estimate the putative disease gene location(s) and expected identical-by-descent allele sharing in affected sib pairs at these gene(s). Extending the work of Liang et...

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PMID: 16193503
DOI: 10.1002/gepi.20094

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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