Article
Tests for the presence of two linked disease susceptibility genes.
Genetic epidemiology - 1 Dec 2005
Biernacka Joanna M, Sun Lei, Bull Shelley B
Abstract excerpt
For diseases with complex genetic etiology, more than one susceptibility gene may exist in a single chromosomal region. Under explicit assumptions about the number of disease genes in a region, generalized estimating equations (GEE) can be used to estimate the putative disease gene location(s) an...
Topics
- Diabetes Mellitus, Type 1
- Genetic Linkage
- Genetic Predisposition to Disease
- Humans
- Likelihood Functions
- Models, Genetic
