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Article

Detection of genome similarity as an exploratory tool for mapping complex traits.

Genetic epidemiology - 1 Jan 1995

Guo S W

Abstract excerpt

For one- and two-trait-locus models, we show that the lod score based on affected relative pairs or trios is a monotonically increasing function of the genome similarity measured by the proportion of alleles shared identical by descent (IBD) conditional on observed marker data. These results can be generalized to multitrait-locus models. Thus, we can use conditional probability of genes shared IBD as a tool to...

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Identifiers

PMID: 8788025
DOI: 10.1002/gepi.1370120658

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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