Article
Evaluation of a new pooling strategy based on leukocyte count for rapid quantification of allele frequencies.
Clinical chemistry - 1 May 2007
Rossmann Heidi, Büchler Elena, Wenzel Jürgen J, Neukirch Carolin, du Prel Jean-Baptist, Lackner Karl J
Abstract excerpt
BACKGROUND: Allele frequencies of single-nucleotide polymorphisms (SNPs) can be quantified from DNA pools. The conventional preparation of DNA pools requires DNA isolation and quantification for each blood sample. We hypothesized that pooling of whole blood samples according to their leukocyte co...
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