Article
DNA pooling and statistical tests for the detection of single nucleotide polymorphisms.
Statistical applications in genetics and molecular biology - 25 Sept 2012
Ramsey David M, Futschik Andreas
Abstract excerpt
The development of next generation genome sequencers gives the opportunity of learning more about the genetic make-up of human and other populations. One important question involves the location of sites at which variation occurs within a population. Our focus will be on the detection of rare variants. Such variants will often not be present in smaller samples and are hard to distinguish from sequencing errors in...
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