Article
Single-nucleotide polymorphism genotyping in DNA pools.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2005
Craig Ian, Meaburn Emma, Butcher Lee, Hill Linzy, Plomin Robert
Abstract excerpt
To undertake partial, or complete, genome screens by association-based methodology for quantitative trait loci, multiple individuals have to be screened for large numbers of genetic markers. Consequently, much recent interest has focused on methods enabling accurate allele quantification in pooled deoxyribonucleic acid (DNA) samples. Microsatellites were the favored markers in initial studies, but the...
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