Article
A simple and accurate method for determination of microsatellite total allele content differences between DNA pools.
Human genetics - 1 Feb 2000
Collins H E, Li H, Inda S E, Anderson J, Laiho K, Tuomilehto J, Seldin M F
Abstract excerpt
DNA pooling is a potential tool for the efficient analysis of the large numbers of samples and DNA markers that are necessary for genome-wide association studies. A simple accurate method for measuring total allele differences in comparisons between two pools containing large numbers of DNA samples is presented. This method compares relative peak height differences between electrophoretograms for each allele of a...
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