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Article

Association of a lithogenic Abcg5/Abcg8 allele on Chromosome 17 (Lith9) with cholesterol gallstone formation in PERA/EiJ mice.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jul 2005

Wittenburg Henning, Lyons Malcolm A, Li Renhua, Kurtz Ulrike, Mössner Joachim, Churchill Gary A, Carey Martin C, Paigen Beverly

Abstract excerpt

To examine further the genetic determinants of cholesterol gallstone susceptibility in inbred mice, we performed quantitative trait locus (QTL) analysis of an intercross of gallstone-susceptible PERA/EiJ and gallstone-resistant DBA/2J inbred mice. Three hundred twenty-four F2 offspring were phenotyped for cholelithiasis during consumption of a lithogenic diet and genotyped using microsatellite markers. Linkage...

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PMID: 16151694
DOI: 10.1007/s00335-005-0006-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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