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Article

Genetic analysis of cholesterol gallstone formation: searching for Lith (gallstone) genes.

Current gastroenterology reports - 1 Apr 2004

Wang David Q-H, Afdhal Nezam H

Abstract excerpt

The genetics of cholesterol cholelithiasis is complex because a number of interacting genes regulate biliary cholesterol homeostasis. Quantitative trait locus (QTL) analysis is a powerful method for identifying primary rate-limiting genetic defects and discriminating them from secondary downstream lithogenic effects caused by mutations of the primary genes. The subsequent positional cloning of such genes...

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Identifiers

PMID: 15191694
DOI: 10.1007/s11894-004-0042-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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