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Article

FXR and ABCG5/ABCG8 as determinants of cholesterol gallstone formation from quantitative trait locus mapping in mice.

Gastroenterology - 1 Sept 2003

Wittenburg Henning, Lyons Malcolm A, Li Renhua, Churchill Gary A, Carey Martin C, Paigen Beverly

Abstract excerpt

BACKGROUND & AIMS: Cholesterol gallstone formation is a complex genetic trait. To identify additional cholesterol gallstone susceptibility loci, we performed a quantitative trait locus analysis using an intercross of PERA/Ei and I/LnJ inbred strains of mice. METHODS: Mice of both sexes were examined for gallstone weight and evaluated according to a scoring system for the physical chemistry of cholelithiasis...

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Source

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PMID: 12949731
DOI: 10.1016/s0016-5085(03)01053-9

Genes

ABCG5
ABCG8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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