Article
[Molecular genetics of cholesterol cholelithiasis: identification of human and murine gallstone genes].
Zeitschrift fur Gastroenterologie - 1 Jun 2002
Figge A, Matern S, Lammert F
Abstract excerpt
Cholesterol cholelithiasis is one of the most common gastroenterological diseases in Western countries. It is a polygenic disease resulting from disturbed biliary cholesterol homeostasis. Association studies identified six human gallstone candidate genes. Polymorphisms in the genes encoding the apolipoproteins B and E, phospholipid flippase ( ABCB4), cholesterol ester transfer protein ( CETP),...
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