Article
QTL mapping for genetic determinants of lipoprotein cholesterol levels in combined crosses of inbred mouse strains.
Journal of lipid research - 1 Aug 2006
Wittenburg Henning, Lyons Malcolm A, Li Renhua, Kurtz Ulrike, Wang Xiaosong, Mössner Joachim, Churchill Gary A, Carey Martin C, Paigen Beverly
Abstract excerpt
To identify additional loci that influence lipoprotein cholesterol levels, we performed quantitative trait locus (QTL) mapping in offspring of PERA/EiJxI/LnJ and PERA/EiJxDBA/2J intercrosses and in a combined data set from both crosses after 8 weeks of consumption of a high fat-diet. Most QTLs identified were concordant with homologous chromosomal regions that were associated with lipoprotein levels in human...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
