Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interacting QTLs for cholesterol gallstones and gallbladder mucin in AKR and SWR strains of mice.

Physiological genomics - 11 Feb 2002

Wittenburg Henning, Lammert Frank, Wang David Q-H, Churchill Gary A, Li Renhua, Bouchard Guylaine, Carey Martin C, Paigen Beverly

Abstract excerpt

We employed quantitative trait locus (QTL) mapping in a backcross between gallstone-susceptible SWR/J and gallstone-resistant AKR/J inbred mice to identify additional susceptibility loci for cholesterol gallstone formation. After 12 wk of feeding the mice a lithogenic diet, we phenotyped 330 backcross progeny for gallstones, gallbladder mucin accumulation, liver weight, and body weight. Marker-based regression...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Weight
Share to Cholelithiasis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gallbladder

Share to Mice, Inbred AKR

Share to Mucins

Share to Organ Size

Share to Quantitative Trait, Heritable

Source

Identifiers

PMID: 11842132
DOI: 10.1152/physiolgenomics.00097.2001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interacting QTLs for cholesterol gallstones and gallbladder mucin in AKR and SWR strains of mice.PMID 11842132Read ↗

Single and interacting QTLs for cholesterol gallstones revealed in an intercross between mouse strains NZB and SM.Semantic proximity Read ↗

Quantitative trait loci mapping for cholesterol gallstones in AKR/J and C57L/J strains of mice.Semantic proximity Read ↗

Lith genes control mucin accumulation, cholesterol crystallization, and gallstone formation in A/J and AKR/J inbred mice.Semantic proximity Read ↗

New quantitative trait loci that contribute to cholesterol gallstone formation detected in an intercross of CAST/Ei and 129S1/SvImJ inbred mice.Semantic proximity Read ↗

Lith1, a major gene affecting cholesterol gallstone formation among inbred strains of mice.Semantic proximity Read ↗

Mapping cholesterol gallstone susceptibility (Lith) genes in inbred mice.Semantic proximity Read ↗

Association of a lithogenic Abcg5/Abcg8 allele on Chromosome 17 (Lith9) with cholesterol gallstone formation in PERA/EiJ mice.Semantic proximity Read ↗

Mouse models of gallstone disease.Semantic proximity Read ↗

FXR and ABCG5/ABCG8 as determinants of cholesterol gallstone formation from quantitative trait locus mapping in mice.Semantic proximity Read ↗

Lith genes and genetic analysis of cholesterol gallstone formation.Semantic proximity Read ↗

Lith6: a new QTL for cholesterol gallstones from an intercross of CAST/Ei and DBA/2J inbred mouse strains.Semantic proximity Read ↗

Genetic analysis of cholesterol gallstone formation: searching for Lith (gallstone) genes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.