Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lith6: a new QTL for cholesterol gallstones from an intercross of CAST/Ei and DBA/2J inbred mouse strains.

Journal of lipid research - 1 Sept 2003

Lyons Malcolm A, Wittenburg Henning, Li Renhua, Walsh Kenneth A, Leonard Monika R, Korstanje Ron, Churchill Gary A, Carey Martin C, Paigen Beverly

Abstract excerpt

A complex genetic basis determines the individual predisposition to develop cholesterol gallstones in response to environmental factors. We employed quantitative trait locus/loci (QTL) analyses of an intercross between inbred strains CAST/Ei (susceptible) and DBA/2J (resistant) to determine the subset of gallstone susceptibility (Lith) genes these strains possess. Parental and first filial generation mice of both...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cholesterol
Share to Chromosomes, Mammalian

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Crosses, Genetic

Share to Gallstones

Share to Mice, Inbred DBA

Share to Mice, Inbred Strains

Share to Quantitative Trait Loci

Source

Identifiers

PMID: 12810825
DOI: 10.1194/jlr.M300149-JLR200

Genes

CAST

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lith6: a new QTL for cholesterol gallstones from an intercross of CAST/Ei and DBA/2J inbred mouse strains.PMID 12810825Read ↗

New quantitative trait loci that contribute to cholesterol gallstone formation detected in an intercross of CAST/Ei and 129S1/SvImJ inbred mice.Semantic proximity Read ↗

Single and interacting QTLs for cholesterol gallstones revealed in an intercross between mouse strains NZB and SM.Semantic proximity Read ↗

Mapping cholesterol gallstone susceptibility (Lith) genes in inbred mice.Semantic proximity Read ↗

Association of a lithogenic Abcg5/Abcg8 allele on Chromosome 17 (Lith9) with cholesterol gallstone formation in PERA/EiJ mice.Semantic proximity Read ↗

Lith genes and genetic analysis of cholesterol gallstone formation.Semantic proximity Read ↗

FXR and ABCG5/ABCG8 as determinants of cholesterol gallstone formation from quantitative trait locus mapping in mice.Semantic proximity Read ↗

Genetic analysis of cholesterol gallstone formation: searching for Lith (gallstone) genes.Semantic proximity Read ↗

High-resolution maps of the murine Chromosome 2 region containing the cholesterol gallstone locus, Lith1.Semantic proximity Read ↗

Quantitative trait loci mapping for cholesterol gallstones in AKR/J and C57L/J strains of mice.Semantic proximity Read ↗

Cholesterol gallstone susceptibility loci: a mouse map, candidate gene evaluation, and guide to human LITH genes.Semantic proximity Read ↗

Interacting QTLs for cholesterol gallstones and gallbladder mucin in AKR and SWR strains of mice.Semantic proximity Read ↗

Lith1, a major gene affecting cholesterol gallstone formation among inbred strains of mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.