Article
An extended association screen in multiple sclerosis using 202 microsatellite markers targeting apoptosis-related genes does not reveal new predisposing factors.
Journal of negative results in biomedicine - 5 Sept 2005
Gödde René, Brune Stefanie, Jagiello Peter, Sindern Eckhart, Haupts Michael, Schimrigk Sebastian, Müller Norbert, Epplen Jörg T
Abstract excerpt
Apoptosis, the programmed death of cells, plays a distinct role in the etiopathogenesis of Multiple sclerosis (MS), a common disease of the central nervous system with complex genetic background. Yet, it is not clear whether the impact of apoptosis is due to altered apoptotic behaviour caused by variations of apoptosis-related genes. Instead, apoptosis in MS may also represent a secondary response to cellular...
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